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Adv Drug Del Rev 55:12611277 Calvillo-Rodrguez KM, Mendoza-Reveles R, Gmez-Morales L, Uscanga-Palomeque AC, Karoyan P, Martnez-Torres AC, Rodrguez-Padilla C (2022) PKHB1, a thrombospondin-1 peptide mimic, induces anti-tumor effect through immunogenic cell death induction in breast cancer cells

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These combined actions have led to interest in its relevance for research models involving cardiovascular stress and impaired circulation.(23) Further animal-based investigations have reported protective effects in models of cardiac injury

Low levels of glutathione can lead to increased oxidative stress and insulin resistance